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NLRC5 Deficiency Deregulates Hepatic Inflammatory Response but Does Not Aggravate Carbon Tetrachloride-Induced Liver Fibrosis

The nucleotide-binding leucine-rich repeat-containing receptor (NLR) family protein-5 (NLRC5) controls NF-κB activation and production of inflammatory cytokines in certain cell types. NLRC5 is considered a potential regulator of hepatic fibrogenic response due to its ability to inhibit hepatic stell...

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Detalles Bibliográficos
Autores principales: Quenum, Akouavi Julite I., Shukla, Akhil, Rexhepi, Fjolla, Cloutier, Maryse, Ghosh, Amit, Kufer, Thomas A., Ramanathan, Sheela, Ilangumaran, Subburaj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546206/
https://www.ncbi.nlm.nih.gov/pubmed/34712238
http://dx.doi.org/10.3389/fimmu.2021.749646