Biophysical Evaluation of Rhesus Macaque Fc Gamma Receptors Reveals Similar IgG Fc Glycoform Preferences to Human Receptors

Rhesus macaques are a common non-human primate model used in the evaluation of human monoclonal antibodies, molecules whose effector functions depend on a conserved N-linked glycan in the Fc region. This carbohydrate is a target of glycoengineering efforts aimed at altering antibody effector functio...

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Detalles Bibliográficos
Autores principales: Crowley, Andrew R., Osei-Owusu, Nana Yaw, Dekkers, Gillian, Gao, Wenda, Wuhrer, Manfred, Magnani, Diogo M., Reimann, Keith A., Pincus, Seth H., Vidarsson, Gestur, Ackerman, Margaret E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546228/
https://www.ncbi.nlm.nih.gov/pubmed/34712242
http://dx.doi.org/10.3389/fimmu.2021.754710

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546228/
https://www.ncbi.nlm.nih.gov/pubmed/34712242
http://dx.doi.org/10.3389/fimmu.2021.754710

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