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Modulating Sirtuin Biology and Nicotinamide Adenine Diphosphate Metabolism in Cardiovascular Disease—From Bench to Bedside

Sirtuins (SIRT1–7) comprise a family of highly conserved deacetylases with distribution in different subcellular compartments. Sirtuins deacetylate target proteins depending on one common substrate, nicotinamide adenine diphosphate (NAD(+)), thus linking their activities to the status of cellular en...

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Detalles Bibliográficos
Autores principales: Wang, Yu-Jen, Paneni, Francesco, Stein, Sokrates, Matter, Christian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546231/
https://www.ncbi.nlm.nih.gov/pubmed/34712151
http://dx.doi.org/10.3389/fphys.2021.755060