The Metabolic Chemical Reporter Ac(4)6AzGal Could Incorporate Intracellular Protein Modification in the Form of UDP-6AzGlc Mediated by OGT and Enzymes in the Leloir Pathway

Galactose is a naturally occurring monosaccharide used to build complex glycans that has not been targeted for labeling as a metabolic reporter. Here, we characterize the cellular modification of proteins by using Ac(4)6AzGal in a dose- and time-dependent manner. It is noted that a vast majority of...

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Detalles Bibliográficos
Autores principales: Wang, Jiajia, Dou, Biao, Zheng, Lu, Cao, Wei, Dong, Peiyu, Chen, Yingyi, Zeng, Xueke, Wen, Yinhang, Pan, Wenxuan, Ma, Jing, Chen, Jingying, Li, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546251/
https://www.ncbi.nlm.nih.gov/pubmed/34712646
http://dx.doi.org/10.3389/fchem.2021.708306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546251/
https://www.ncbi.nlm.nih.gov/pubmed/34712646
http://dx.doi.org/10.3389/fchem.2021.708306

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