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The Metabolic Chemical Reporter Ac(4)6AzGal Could Incorporate Intracellular Protein Modification in the Form of UDP-6AzGlc Mediated by OGT and Enzymes in the Leloir Pathway
Galactose is a naturally occurring monosaccharide used to build complex glycans that has not been targeted for labeling as a metabolic reporter. Here, we characterize the cellular modification of proteins by using Ac(4)6AzGal in a dose- and time-dependent manner. It is noted that a vast majority of...
| Autores principales: | , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546251/ https://www.ncbi.nlm.nih.gov/pubmed/34712646 http://dx.doi.org/10.3389/fchem.2021.708306 |