Structural characteristics of Heparan sulfate required for the binding with the virus processing Enzyme Furin

Furin is one of the nine-member proprotein convertase family. Furin cleaves proteins with polybasic residues, which includes many viral glycoproteins such as SARS-Cov-2 spike protein. The cleavage is required for the activation of the proteins. Currently, the mechanisms that regulate Furin activity...

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Detalles Bibliográficos
Autores principales: Zeng, Jiaxin, Meng, Yuan, Chen, Shi-Yi, Zhao, Gaofeng, Wang, Lianchun, Zhang, En-Xin, Qiu, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546381/
https://www.ncbi.nlm.nih.gov/pubmed/34699015
http://dx.doi.org/10.1007/s10719-021-10018-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546381/
https://www.ncbi.nlm.nih.gov/pubmed/34699015
http://dx.doi.org/10.1007/s10719-021-10018-8

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