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Structural characteristics of Heparan sulfate required for the binding with the virus processing Enzyme Furin
Furin is one of the nine-member proprotein convertase family. Furin cleaves proteins with polybasic residues, which includes many viral glycoproteins such as SARS-Cov-2 spike protein. The cleavage is required for the activation of the proteins. Currently, the mechanisms that regulate Furin activity...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546381/ https://www.ncbi.nlm.nih.gov/pubmed/34699015 http://dx.doi.org/10.1007/s10719-021-10018-8 |