CK2 Phosphorylation of Human Papillomavirus 16 E2 on Serine 23 Promotes Interaction with TopBP1 and Is Critical for E2 Interaction with Mitotic Chromatin and the Viral Life Cycle

During the human papillomavirus 16 (HPV16) life cycle, the E2 protein interacts with host factors to regulate viral transcription, replication, and genome segregation/retention. Our understanding of host partner proteins and their roles in E2 functions remains incomplete. Here we demonstrate that CK...

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Detalles Bibliográficos
Autores principales: Prabhakar, Apurva T., James, Claire D., Das, Dipon, Otoa, Raymonde, Day, Matthew, Burgner, John, Fontan, Christian T., Wang, Xu, Glass, Sarah H., Wieland, Andreas, Donaldson, Mary M., Bristol, Molly L., Li, Renfeng, Oliver, Anthony W., Pearl, Laurence H., Smith, Brian O., Morgan, Iain M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546539/
https://www.ncbi.nlm.nih.gov/pubmed/34544280
http://dx.doi.org/10.1128/mBio.01163-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546539/
https://www.ncbi.nlm.nih.gov/pubmed/34544280
http://dx.doi.org/10.1128/mBio.01163-21

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