Across Functional Boundaries: Making Nonneutralizing Antibodies To Neutralize HIV-1 and Mediate Fc-Mediated Effector Killing of Infected Cells

In HIV-1 infection, many antibodies (Abs) are elicited to Envelope (Env) epitopes that are conformationally masked in the native trimer and are only available for antibody recognition after the trimer binds host cell CD4. Among these are epitopes within the Co-Receptor Binding Site (CoRBS) and the c...

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Detalles Bibliográficos
Autores principales: Richard, Jonathan, Nguyen, Dung N., Tolbert, William D., Gasser, Romain, Ding, Shilei, Vézina, Dani, Yu Gong, Shang, Prévost, Jérémie, Gendron-Lepage, Gabrielle, Medjahed, Halima, Gottumukkala, Suneetha, Finzi, Andrés, Pazgier, Marzena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546553/
https://www.ncbi.nlm.nih.gov/pubmed/34579568
http://dx.doi.org/10.1128/mBio.01405-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546553/
https://www.ncbi.nlm.nih.gov/pubmed/34579568
http://dx.doi.org/10.1128/mBio.01405-21

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