Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha

Human cytomegalovirus (HCMV) is a herpesvirus that produces disease in transplant patients and newborn children. Entry of HCMV into cells relies on gH/gL trimer (gHgLgO) and pentamer (gHgLUL128–131) complexes that bind cellular receptors. Here, we studied the structure and interactions of the HCMV t...

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Detalles Bibliográficos
Autores principales: Liu, Jing, Vanarsdall, Adam, Chen, Dong-Hua, Chin, Andrea, Johnson, David, Jardetzky, Theodore S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546573/
https://www.ncbi.nlm.nih.gov/pubmed/34700375
http://dx.doi.org/10.1128/mBio.02625-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546573/
https://www.ncbi.nlm.nih.gov/pubmed/34700375
http://dx.doi.org/10.1128/mBio.02625-21

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