HIV-1 Genomes Are Enriched in Memory CD4(+) T-Cells with Short Half-Lives

Future HIV-1 curative therapies require a thorough understanding of the distribution of genetically-intact HIV-1 within T-cell subsets during antiretroviral therapy (ART) and the cellular mechanisms that maintain this reservoir. Therefore, we sequenced near-full-length HIV-1 genomes and identified g...

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Detalles Bibliográficos
Autores principales: Morcilla, Vincent, Bacchus-Souffan, Charline, Fisher, Katie, Horsburgh, Bethany A., Hiener, Bonnie, Wang, Xiao Qian, Schlub, Timothy E., Fitch, Mark, Hoh, Rebecca, Hecht, Frederick M., Martin, Jeffrey N., Deeks, Steven G., Hellerstein, Marc K., McCune, Joseph M., Hunt, Peter W., Palmer, Sarah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546577/
https://www.ncbi.nlm.nih.gov/pubmed/34544282
http://dx.doi.org/10.1128/mBio.02447-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546577/
https://www.ncbi.nlm.nih.gov/pubmed/34544282
http://dx.doi.org/10.1128/mBio.02447-21

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