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HIV-1 Genomes Are Enriched in Memory CD4(+) T-Cells with Short Half-Lives
Future HIV-1 curative therapies require a thorough understanding of the distribution of genetically-intact HIV-1 within T-cell subsets during antiretroviral therapy (ART) and the cellular mechanisms that maintain this reservoir. Therefore, we sequenced near-full-length HIV-1 genomes and identified g...
Autores principales: | Morcilla, Vincent, Bacchus-Souffan, Charline, Fisher, Katie, Horsburgh, Bethany A., Hiener, Bonnie, Wang, Xiao Qian, Schlub, Timothy E., Fitch, Mark, Hoh, Rebecca, Hecht, Frederick M., Martin, Jeffrey N., Deeks, Steven G., Hellerstein, Marc K., McCune, Joseph M., Hunt, Peter W., Palmer, Sarah |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546577/ https://www.ncbi.nlm.nih.gov/pubmed/34544282 http://dx.doi.org/10.1128/mBio.02447-21 |
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