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LncRNA XR_001779380 Primes Epithelial Cells for IFN-γ-Mediated Gene Transcription and Facilitates Age-Dependent Intestinal Antimicrobial Defense

Interferon (IFN) signaling is key to mucosal immunity in the gastrointestinal tract, but cellular regulatory elements that determine interferon gamma (IFN-γ)-mediated antimicrobial defense in intestinal epithelial cells are not fully understood. We report here that a long noncoding RNA (lncRNA), Gen...

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Detalles Bibliográficos
Autores principales: Gong, Ai-Yu, Wang, Yang, Li, Min, Zhang, Xin-Tian, Deng, Silu, Chen, Jessie M., Lu, Eugene, Mathy, Nicholas W., Martins, Gislaine A., Strauss-Soukup, Juliane K., Chen, Xian-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546593/
https://www.ncbi.nlm.nih.gov/pubmed/34488445
http://dx.doi.org/10.1128/mBio.02127-21