Rational gRNA design based on transcription factor binding data

The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system has become a standard tool in many genome engineering endeavors. The endonuclease-deficient version of Cas9 (dCas9) is also a powerful programmable tool for gene regulation. In this study, we made use of Saccharomyces...

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Detalles Bibliográficos
Autores principales: Bergenholm, David, Dabirian, Yasaman, Ferreira, Raphael, Siewers, Verena, David, Florian, Nielsen, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546606/
https://www.ncbi.nlm.nih.gov/pubmed/34712839
http://dx.doi.org/10.1093/synbio/ysab014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546606/
https://www.ncbi.nlm.nih.gov/pubmed/34712839
http://dx.doi.org/10.1093/synbio/ysab014

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