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Trypanosoma brucei Tim50 Possesses PAP Activity and Plays a Critical Role in Cell Cycle Regulation and Parasite Infectivity

Trypanosoma brucei, the infective agent for African trypanosomiasis, possesses a homologue of the translocase of the mitochondrial inner membrane 50 (TbTim50). It has a pair of characteristic phosphatase signature motifs, DXDX(T/V). Here, we demonstrated that, besides its protein phosphatase activit...

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Detalles Bibliográficos
Autores principales: Tripathi, Anuj, Singha, Ujjal K., Cooley, Ayorinde, Gillyard, Taneisha, Krystofiak, Evan, Pratap, Siddharth, Davis, Jamaine, Chaudhuri, Minu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546626/
https://www.ncbi.nlm.nih.gov/pubmed/34517757
http://dx.doi.org/10.1128/mBio.01592-21