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Original Antigenic Sin: the Downside of Immunological Memory and Implications for COVID-19

The concept of original antigenic sin (OAS) was put forth many years ago to explain how humoral memory responses generated against one set of antigens can affect the nature of antibody responses elicited to challenge infections or vaccinations containing a similar but not identical array of antigens...

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Detalles Bibliográficos
Autores principales: Brown, Eric L., Essigmann, Heather T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546681/
https://www.ncbi.nlm.nih.gov/pubmed/33692194
http://dx.doi.org/10.1128/mSphere.00056-21