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A Point Mutation in the Transcriptional Repressor PerR Results in a Constitutive Oxidative Stress Response in Clostridioides difficile 630Δerm

The human pathogen Clostridioides difficile has evolved into the leading cause of nosocomial diarrhea. The bacterium is capable of spore formation, which even allows survival of antibiotic treatment. Although C. difficile features an anaerobic lifestyle, we determined a remarkably high oxygen tolera...

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Detalles Bibliográficos
Autores principales: Troitzsch, Daniel, Zhang, Hao, Dittmann, Silvia, Düsterhöft, Dorothee, Möller, Timon Alexander, Michel, Annika-Marisa, Jänsch, Lothar, Riedel, Katharina, Borrero-de Acuña, José Manuel, Jahn, Dieter, Sievers, Susanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546684/
https://www.ncbi.nlm.nih.gov/pubmed/33658275
http://dx.doi.org/10.1128/mSphere.00091-21