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B Cell Receptor-Responsive miR-141 Enhances Epstein-Barr Virus Lytic Cycle via FOXO3 Inhibition

Antigen recognition by the B cell receptor (BCR) is a physiological trigger for reactivation of Epstein-Barr virus (EBV) and can be recapitulated in vitro by cross-linking of surface immunoglobulins. Previously, we identified a subset of EBV microRNAs (miRNAs) that attenuate BCR signal transduction...

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Detalles Bibliográficos
Autores principales: Chen, Yan, Fachko, Devin N., Ivanov, Nikita S., Skalsky, Rebecca L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546685/
https://www.ncbi.nlm.nih.gov/pubmed/33853871
http://dx.doi.org/10.1128/mSphere.00093-21