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Ehrlichia chaffeensis TRP120 Is a Wnt Ligand Mimetic That Interacts with Wnt Receptors and Contains a Novel Repetitive Short Linear Motif That Activates Wnt Signaling

Ehrlichia chaffeensis expresses the TRP120 multifunctional effector, which is known to play a role in phagocytic entry, on the surface of infectious dense-cored ehrlichiae, but a cognate host receptor has not been identified. We recently reported that E. chaffeensis activates canonical Wnt signaling...

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Detalles Bibliográficos
Autores principales: Rogan, Madison R., Patterson, LaNisha L., Byerly, Caitlan D., Luo, Tian, Paessler, Slobodan, Veljkovic, Veljko, Quade, Bethany, McBride, Jere W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546699/
https://www.ncbi.nlm.nih.gov/pubmed/33883266
http://dx.doi.org/10.1128/mSphere.00216-21