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Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases in the Prevention of Experimental Invasive Aspergillosis

Aspergillus fumigatus is a ubiquitous mold that can cause invasive pulmonary infections in immunocompromised patients. Within the lung, A. fumigatus forms biofilms that can enhance resistance to antifungals and immune defenses. Aspergillus biofilm formation requires the production of a cationic matr...

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Detalles Bibliográficos
Autores principales: Ostapska, Hanna, Raju, Deepa, Lehoux, Melanie, Lacdao, Ira, Gilbert, Stephanie, Sivarajah, Piyanka, Bamford, Natalie C., Baker, Perrin, Nguyen, Thi Tuyet Mai, Zacharias, Caitlin A., Gravelat, Fabrice N., Howell, P. Lynne, Sheppard, Donald C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546845/
https://www.ncbi.nlm.nih.gov/pubmed/34579578
http://dx.doi.org/10.1128/mBio.02446-21