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Preclinical Evaluation of Recombinant Microbial Glycoside Hydrolases in the Prevention of Experimental Invasive Aspergillosis
Aspergillus fumigatus is a ubiquitous mold that can cause invasive pulmonary infections in immunocompromised patients. Within the lung, A. fumigatus forms biofilms that can enhance resistance to antifungals and immune defenses. Aspergillus biofilm formation requires the production of a cationic matr...
Autores principales: | Ostapska, Hanna, Raju, Deepa, Lehoux, Melanie, Lacdao, Ira, Gilbert, Stephanie, Sivarajah, Piyanka, Bamford, Natalie C., Baker, Perrin, Nguyen, Thi Tuyet Mai, Zacharias, Caitlin A., Gravelat, Fabrice N., Howell, P. Lynne, Sheppard, Donald C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546845/ https://www.ncbi.nlm.nih.gov/pubmed/34579578 http://dx.doi.org/10.1128/mBio.02446-21 |
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