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Mechanism of Microbial Metabolite Leupeptin in the Treatment of COVID-19 by Traditional Chinese Medicine Herbs

Coronavirus disease 2019 (COVID-19) has caused huge deaths and economic losses worldwide in the current pandemic. The main protease (M(pro)) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is thought to be an ideal drug target for treating COVID-19. Leupeptin, a broad-spectrum covale...

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Detalles Bibliográficos
Autores principales: Fu, Lifeng, Shao, Shuai, Feng, Yong, Ye, Fei, Sun, Xue, Wang, Qingling, Yu, Feng, Wang, Qisheng, Huang, Baoying, Niu, Peihua, Li, Xuebing, Wong, Catherine C. L., Qi, Jianxun, Tan, Wenjie, Gao, George Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546846/
https://www.ncbi.nlm.nih.gov/pubmed/34579576
http://dx.doi.org/10.1128/mBio.02220-21