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Antibody-Dependent Enhancement of SARS-CoV-2 Infection Is Mediated by the IgG Receptors FcγRIIA and FcγRIIIA but Does Not Contribute to Aberrant Cytokine Production by Macrophages

The coronavirus disease 2019 (COVID-19) pandemic has raised concerns about the detrimental effects of antibodies. Antibody-dependent enhancement (ADE) of infection is one of the biggest concerns in terms of not only the antibody reaction to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2...

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Detalles Bibliográficos
Autores principales: Maemura, Tadashi, Kuroda, Makoto, Armbrust, Tammy, Yamayoshi, Seiya, Halfmann, Peter J., Kawaoka, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546849/
https://www.ncbi.nlm.nih.gov/pubmed/34579572
http://dx.doi.org/10.1128/mBio.01987-21