The Tumor Necrosis Factor Alpha and Interleukin 6 Auto-paracrine Signaling Loop Controls Mycobacterium avium Infection via Induction of IRF1/IRG1 in Human Primary Macrophages

Macrophages sense and respond to pathogens by induction of antimicrobial and inflammatory programs to alert other immune cells and eliminate the infectious threat. We have previously identified the transcription factor IRF1 to be consistently activated in macrophages during Mycobacterium avium infec...

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Detalles Bibliográficos
Autores principales: Gidon, Alexandre, Louet, Claire, Røst, Lisa Marie, Bruheim, Per, Flo, Trude Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546851/
https://www.ncbi.nlm.nih.gov/pubmed/34607464
http://dx.doi.org/10.1128/mBio.02121-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546851/
https://www.ncbi.nlm.nih.gov/pubmed/34607464
http://dx.doi.org/10.1128/mBio.02121-21

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