3D disorganization and rearrangement of genome provide insights into pathogenesis of NAFLD by integrated Hi-C, Nanopore, and RNA sequencing

The three-dimensional (3D) conformation of chromatin is integral to the precise regulation of gene expression. The 3D genome and genomic variations in non-alcoholic fatty liver disease (NAFLD) are largely unknown, despite their key roles in cellular function and physiological processes. High-through...

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Detalles Bibliográficos
Autores principales: Xu, Lina, Yin, Lianhong, Qi, Yan, Tan, Xuemei, Gao, Meng, Peng, Jinyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546856/
https://www.ncbi.nlm.nih.gov/pubmed/34729306
http://dx.doi.org/10.1016/j.apsb.2021.03.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546856/
https://www.ncbi.nlm.nih.gov/pubmed/34729306
http://dx.doi.org/10.1016/j.apsb.2021.03.022

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