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Commensal-Related Changes in the Epidermal Barrier Function Lead to Alterations in the Benzo[a]Pyrene Metabolite Profile and Its Distribution in 3D Skin

Polycyclic aromatic hydrocarbons (PAH) such as benzo[a]pyrene (B[a]P) are among the most abundant environmental pollutants, resulting in continuous exposure of human skin and its microbiota. However, effects of the latter on B[a]P toxicity, absorption, metabolism, and distribution in humans remain u...

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Detalles Bibliográficos
Autores principales: Lemoine, Lisa, Bayrambey, Dilan, Roloff, Alexander, Hutzler, Christoph, Luch, Andreas, Tralau, Tewes
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546866/
https://www.ncbi.nlm.nih.gov/pubmed/34579573
http://dx.doi.org/10.1128/mBio.01223-21