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Metabolomic Analysis of Diverse Mice Reveals Hepatic Arginase-1 as Source of Plasma Arginase in Plasmodium chabaudi Infection

Infections disrupt host metabolism, but the factors that dictate the nature and magnitude of metabolic change are incompletely characterized. To determine how host metabolism changes in relation to disease severity in murine malaria, we performed plasma metabolomics on eight Plasmodium chabaudi-infe...

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Detalles Bibliográficos
Autores principales: Davis, Nicole M., Lissner, Michelle M., Richards, Crystal L., Chevée, Victoria, Gupta, Avni S., Gherardini, Frank C., Schneider, David S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546868/
https://www.ncbi.nlm.nih.gov/pubmed/34607466
http://dx.doi.org/10.1128/mBio.02424-21