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Sputum Proteome Signatures of Mechanically Ventilated Intensive Care Unit Patients Distinguish Samples with or without Anti-pneumococcal Activity

Mechanically ventilated patients are at risk of contracting pneumonia. Therefore, these patients often receive prophylactic systemic antimicrobial therapy. Intriguingly however, a previous study showed that antimicrobial activity in bronchoalveolar aspirates (here referred to as “sputa”) from ventil...

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Detalles Bibliográficos
Autores principales: Seinen, Jolien, Engelke, Rudolf, Abdullah, Mohammed R., Voß, Franziska, Michalik, Stephan, Dhople, Vishnu M., Dieperink, Willem, de Smet, Anne Marie G. A., Völker, Uwe, van Dijl, Jan Maarten, Schmidt, Frank, Hammerschmidt, Sven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8546979/
https://www.ncbi.nlm.nih.gov/pubmed/33653939
http://dx.doi.org/10.1128/mSystems.00702-20