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Fecal Microbiome Transplantation from Children with Autism Spectrum Disorder Modulates Tryptophan and Serotonergic Synapse Metabolism and Induces Altered Behaviors in Germ-Free Mice

To determine the relationship of the gut microbiota and its metabolites with autism spectrum disorder (ASD)-like behaviors and preliminarily explore the potential molecular mechanisms, the fecal microbiota from donors with ASD and typically developing (TD) donors were transferred into germ-free (GF)...

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Detalles Bibliográficos
Autores principales: Xiao, Lu, Yan, Junyan, Yang, Ting, Zhu, Jiang, Li, Tingyu, Wei, Hong, Chen, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547010/
https://www.ncbi.nlm.nih.gov/pubmed/33824200
http://dx.doi.org/10.1128/mSystems.01343-20