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Utility of droplet digital polymerase chain reaction for TERT and BRAF mutational profiling of thyroid nodules

BACKGROUND: Mutations involving BRAF and TERT are important predictors of disease severity in thyroid cancer, but molecular testing is limited by cost and lack of adequate tissue sample. This study aimed to assess the utility of BRAFV600E and TERT testing using droplet digital PCR (ddPCR) as a diagn...

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Detalles Bibliográficos
Autores principales: Rosvall, Brandon R., Kostiuk, Morris, Williams, Jordana, Matkin, Ashlee, Harris, Jeffrey, Seikaly, Hadi, O’Connell, Daniel A., Biron, Vincent L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547072/
https://www.ncbi.nlm.nih.gov/pubmed/34702207
http://dx.doi.org/10.1186/s12885-021-08810-8