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Utility of droplet digital polymerase chain reaction for TERT and BRAF mutational profiling of thyroid nodules
BACKGROUND: Mutations involving BRAF and TERT are important predictors of disease severity in thyroid cancer, but molecular testing is limited by cost and lack of adequate tissue sample. This study aimed to assess the utility of BRAFV600E and TERT testing using droplet digital PCR (ddPCR) as a diagn...
Autores principales: | Rosvall, Brandon R., Kostiuk, Morris, Williams, Jordana, Matkin, Ashlee, Harris, Jeffrey, Seikaly, Hadi, O’Connell, Daniel A., Biron, Vincent L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547072/ https://www.ncbi.nlm.nih.gov/pubmed/34702207 http://dx.doi.org/10.1186/s12885-021-08810-8 |
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