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Lnc-PFAR facilitates autophagy and exacerbates pancreatic fibrosis by reducing pre-miR-141 maturation in chronic pancreatitis

Chronic pancreatitis (CP) is described as progressive inflammatory fibrosis of pancreas, accompanied with irreversible impaired endocrine and exocrine insufficiency. Pancreatic stellate cells (PSCs) are widely distributed in the stroma of the pancreas and PSCs activation has been shown as one of the...

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Detalles Bibliográficos
Autores principales: Zhang, Tao, Zhang, Guangquan, Yang, Wenbo, Chen, Hongze, Hu, Jisheng, Zhao, Zhongjie, Cheng, Chundong, Li, Guanqun, Xie, Yu, Li, Yilong, Kong, Rui, Wang, Yongwei, Wang, Gang, Chen, Hua, Bai, Xue-Wei, Pan, Shangha, Sun, Bei, Li, Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547218/
https://www.ncbi.nlm.nih.gov/pubmed/34697288
http://dx.doi.org/10.1038/s41419-021-04236-z