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The β(3) Adrenergic Receptor Antagonist L-748,337 Attenuates Dobutamine-Induced Cardiac Inefficiency While Preserving Inotropy in Anesthetized Pigs
Excessive myocardial oxygen consumption (MVO(2)) is considered a limitation for catecholamines, termed oxygen cost of contractility. We hypothesize that increased MVO(2) induced by dobutamine is not directly related to contractility but linked to intermediary myocardial metabolism. Furthermore, we h...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547236/ https://www.ncbi.nlm.nih.gov/pubmed/34551626 http://dx.doi.org/10.1177/10742484211048762 |