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The β(3) Adrenergic Receptor Antagonist L-748,337 Attenuates Dobutamine-Induced Cardiac Inefficiency While Preserving Inotropy in Anesthetized Pigs

Excessive myocardial oxygen consumption (MVO(2)) is considered a limitation for catecholamines, termed oxygen cost of contractility. We hypothesize that increased MVO(2) induced by dobutamine is not directly related to contractility but linked to intermediary myocardial metabolism. Furthermore, we h...

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Detalles Bibliográficos
Autores principales: Rødland, Lars, Rønning, Leif, Kildal, Anders Benjamin, How, Ole-Jakob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547236/
https://www.ncbi.nlm.nih.gov/pubmed/34551626
http://dx.doi.org/10.1177/10742484211048762