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Timing RNA polymerase pausing with TV-PRO-seq

Transcription of many genes in metazoans is subject to polymerase pausing, which is the transient stop of transcriptionally engaged polymerases. This is known to mainly occur in promoter-proximal regions but it is not well understood. In particular, a genome-wide measurement of pausing times at high...

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Detalles Bibliográficos
Autores principales: Zhang, Jie, Cavallaro, Massimo, Hebenstreit, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547241/
https://www.ncbi.nlm.nih.gov/pubmed/34723238
http://dx.doi.org/10.1016/j.crmeth.2021.100083