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A dynamic microscale mid-throughput fibrosis model to investigate the effects of different ratios of cardiomyocytes and fibroblasts

Cardiac fibrosis is a maladaptive remodeling of the myocardium hallmarked by contraction impairment and excessive extracellular matrix deposition (ECM). The disease progression, nevertheless, remains poorly understood and present treatments are not capable of controlling the scarring process. This i...

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Detalles Bibliográficos
Autores principales: Mainardi, Andrea, Carminati, Francesca, Ugolini, Giovanni Stefano, Occhetta, Paola, Isu, Giuseppe, Robles Diaz, Diana, Reid, Gregory, Visone, Roberta, Rasponi, Marco, Marsano, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547330/
https://www.ncbi.nlm.nih.gov/pubmed/34545378
http://dx.doi.org/10.1039/d1lc00092f