Building Natural Product Libraries Using Quantitative Clade-Based and Chemical Clustering Strategies

The success of natural product-based drug discovery is predicated on having chemical collections that offer broad coverage of metabolite diversity. We propose a simple set of tools combining genetic barcoding and metabolomics to help investigators build natural product libraries aimed at achieving p...

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Detalles Bibliográficos
Autores principales: Anderson, Victoria M., Wendt, Karen L., Najar, Fares Z., McCall, Laura-Isobel, Cichewicz, Robert H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547436/
https://www.ncbi.nlm.nih.gov/pubmed/34698546
http://dx.doi.org/10.1128/mSystems.00644-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547436/
https://www.ncbi.nlm.nih.gov/pubmed/34698546
http://dx.doi.org/10.1128/mSystems.00644-21

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