Transcriptional and Post-Transcriptional Polar Effects in Bacterial Gene Deletion Libraries

Single-gene deletions can affect the expression levels of other genes in the same operon in bacterial genomes. Here, we used proteomics for 133 Escherichia coli gene deletion mutants and transcriptome sequencing (RNA-seq) data from 71 mutants to probe the extent of transcriptional and post-transcrip...

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Detalles Bibliográficos
Autores principales: Mateus, André, Shah, Malay, Hevler, Johannes, Kurzawa, Nils, Bobonis, Jacob, Typas, Athanasios, Savitski, Mikhail M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2021
Materias:
Observation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547470/
https://www.ncbi.nlm.nih.gov/pubmed/34491080
http://dx.doi.org/10.1128/mSystems.00813-21

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547470/
https://www.ncbi.nlm.nih.gov/pubmed/34491080
http://dx.doi.org/10.1128/mSystems.00813-21

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