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Transcriptional and Post-Transcriptional Polar Effects in Bacterial Gene Deletion Libraries
Single-gene deletions can affect the expression levels of other genes in the same operon in bacterial genomes. Here, we used proteomics for 133 Escherichia coli gene deletion mutants and transcriptome sequencing (RNA-seq) data from 71 mutants to probe the extent of transcriptional and post-transcrip...
Autores principales: | Mateus, André, Shah, Malay, Hevler, Johannes, Kurzawa, Nils, Bobonis, Jacob, Typas, Athanasios, Savitski, Mikhail M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547470/ https://www.ncbi.nlm.nih.gov/pubmed/34491080 http://dx.doi.org/10.1128/mSystems.00813-21 |
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