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A Thermostable Cas12b from Brevibacillus Leverages One-pot Detection of SARS-CoV-2 Variants of Concern

Current SARS-CoV-2 detection platforms lack the ability to differentiate among variants of concern (VOCs) in an efficient manner. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) has the potential to transform diagnostics due to its programmability. However, many of the CRISPR-base...

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Detalles Bibliográficos
Autores principales: Nguyen, Long T., Macaluso, Nicolas C., Pizzano, Brianna L.M., Cash, Melanie N., Spacek, Jan, Karasek, Jan, Dinglasan, Rhoel R., Salemi, Marco, Jain, Piyush K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547533/
https://www.ncbi.nlm.nih.gov/pubmed/34704101
http://dx.doi.org/10.1101/2021.10.15.21265066