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A Thermostable Cas12b from Brevibacillus Leverages One-pot Detection of SARS-CoV-2 Variants of Concern
Current SARS-CoV-2 detection platforms lack the ability to differentiate among variants of concern (VOCs) in an efficient manner. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) has the potential to transform diagnostics due to its programmability. However, many of the CRISPR-base...
Autores principales: | Nguyen, Long T., Macaluso, Nicolas C., Pizzano, Brianna L.M., Cash, Melanie N., Spacek, Jan, Karasek, Jan, Dinglasan, Rhoel R., Salemi, Marco, Jain, Piyush K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547533/ https://www.ncbi.nlm.nih.gov/pubmed/34704101 http://dx.doi.org/10.1101/2021.10.15.21265066 |
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