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Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole-kindled mice

Epilepsy comorbidities and anti-epileptic drugs (AEDs) are currently the main limitations of epilepsy treatment. Semaglutide is a glucagon like peptide-1 analogue that has entered the market as a new once-weekly drug for type II diabetes. The aim of the present study was to investigate the functions...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Ding, Jiangwei, Zhu, Changliang, Guo, Baorui, Yang, Wu, He, Wenxin, Li, Xinxiao, Wang, Yangyang, Li, Wenchao, Wang, Feng, Sun, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547541/
https://www.ncbi.nlm.nih.gov/pubmed/34676876
http://dx.doi.org/10.3892/ijmm.2021.5052