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Semaglutide attenuates seizure severity and ameliorates cognitive dysfunction by blocking the NLR family pyrin domain containing 3 inflammasome in pentylenetetrazole-kindled mice
Epilepsy comorbidities and anti-epileptic drugs (AEDs) are currently the main limitations of epilepsy treatment. Semaglutide is a glucagon like peptide-1 analogue that has entered the market as a new once-weekly drug for type II diabetes. The aim of the present study was to investigate the functions...
Autores principales: | Wang, Lei, Ding, Jiangwei, Zhu, Changliang, Guo, Baorui, Yang, Wu, He, Wenxin, Li, Xinxiao, Wang, Yangyang, Li, Wenchao, Wang, Feng, Sun, Tao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547541/ https://www.ncbi.nlm.nih.gov/pubmed/34676876 http://dx.doi.org/10.3892/ijmm.2021.5052 |
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