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Molecular and cellular mechanisms of spastin in neural development and disease (Review)

Spastin is a microtubule (MT)-severing enzyme identified from mutations of hereditary spastic paraplegia in 1999 and extensive studies indicate its vital role in various cellular activities. In the past two decades, efforts have been made to understand the underlying molecular mechanisms of how spas...

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Detalles Bibliográficos
Autores principales: Liu, Qiuling, Zhang, Guowei, Ji, Zhisheng, Lin, Hongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547542/
https://www.ncbi.nlm.nih.gov/pubmed/34664680
http://dx.doi.org/10.3892/ijmm.2021.5051