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Effects of acetazolamide on control of breathing in sleep apnea patients: Mechanistic insights using meta‐analyses and physiological model simulations

Obstructive and central sleep apnea affects ~1 billion people globally and may lead to serious cardiovascular and neurocognitive consequences, but treatment options are limited. High loop gain (ventilatory instability) is a major pathophysiological mechanism underlying both types of sleep apnea and...

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Detalles Bibliográficos
Autores principales: Schmickl, Christopher N., Landry, Shane, Orr, Jeremy E., Nokes, Brandon, Edwards, Bradley A., Malhotra, Atul, Owens, Robert L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547551/
https://www.ncbi.nlm.nih.gov/pubmed/34699135
http://dx.doi.org/10.14814/phy2.15071