Integrating single cell sequencing with a spatial quantitative systems pharmacology model spQSP for personalized prediction of triple-negative breast cancer immunotherapy response

Response to cancer immunotherapies depends on the complex and dynamic interactions between T cell recognition and killing of cancer cells that are counteracted through immunosuppressive pathways in the tumor microenvironment. Therefore, while measurements such as tumor mutational burden provide biom...

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Detalles Bibliográficos
Autores principales: Zhang, Shuming, Gong, Chang, Ruiz-Martinez, Alvaro, Wang, Hanwen, Davis-Marcisak, Emily, Deshpande, Atul, Popel, Aleksander S., Fertig, Elana J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547770/
https://www.ncbi.nlm.nih.gov/pubmed/34708216
http://dx.doi.org/10.1016/j.immuno.2021.100002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547770/
https://www.ncbi.nlm.nih.gov/pubmed/34708216
http://dx.doi.org/10.1016/j.immuno.2021.100002

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