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Simultaneous measurement of tadehaginoside and its principal metabolite in rats by HPLC–MS/MS and its application in pharmacokinetics and tissue distribution study

CONTEXT: Tadehaginoside, an active ingredient isolated from Tadehagi triquetrum (Linn.) Ohashi (Leguminosae), exhibited various biological activities. However, the pharmacokinetics and tissue distribution which affect tadehaginoside’s therapeutic actions and application remain elusive. OBJECTIVE: To...

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Detalles Bibliográficos
Autores principales: Zhang, Cai-Yun, Lu, Ya-Ting, Tan, Yin-Feng, Liu, Qi-Bing, Dong, Lin, Ma, Ning, Lu, Wei-Ying, Su, Zhi-Heng, Zhang, Xiao-Po
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547841/
https://www.ncbi.nlm.nih.gov/pubmed/34689683
http://dx.doi.org/10.1080/13880209.2021.1990354