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Principles for designing an optimal mRNA lipid nanoparticle vaccine

mRNA Lipid nanoparticles (LNPs) have recently been propelled onto the center stage of therapeutic platforms due to the success of the SARS-CoV-2 mRNA LNP vaccines (mRNA-1273 and BNT162b2), with billions of mRNA vaccine doses already shipped worldwide. While mRNA vaccines seem like an overnight succe...

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Detalles Bibliográficos
Autores principales: Kon, Edo, Elia, Uri, Peer, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547895/
https://www.ncbi.nlm.nih.gov/pubmed/34715546
http://dx.doi.org/10.1016/j.copbio.2021.09.016