PARP Inhibition in Prostate Cancer With Homologous Recombination Repair Alterations

PURPOSE: With the broad use of next-generation sequencing assays, it has become clear that mutations in DNA repair genes are more commonly found than previously reported. In advanced prostate cancer patients with BRCA1/2 or ATM mutations, poly (ADP-ribose) polymerase inhibition (PARPi) causes an inc...

Descripción completa

Detalles Bibliográficos
Autores principales: von Werdt, Alexander, Brandt, Laura, Schärer, Orlando D., Rubin, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2021
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547927/
https://www.ncbi.nlm.nih.gov/pubmed/34712892
http://dx.doi.org/10.1200/PO.21.00152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547927/
https://www.ncbi.nlm.nih.gov/pubmed/34712892
http://dx.doi.org/10.1200/PO.21.00152

Ejemplares similares