Fascin limits Myosin activity within Drosophila border cells to control substrate stiffness and promote migration

A key regulator of collective cell migrations, which drive development and cancer metastasis, is substrate stiffness. Increased substrate stiffness promotes migration and is controlled by Myosin. Using Drosophila border cell migration as a model of collective cell migration, we identify, for the fir...

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Detalles Bibliográficos
Autores principales: Lamb, Maureen C, Kaluarachchi, Chathuri P, Lansakara, Thiranjeewa I, Mellentine, Samuel Q, Lan, Yiling, Tivanski, Alexei V, Tootle, Tina L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547955/
https://www.ncbi.nlm.nih.gov/pubmed/34698017
http://dx.doi.org/10.7554/eLife.69836

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547955/
https://www.ncbi.nlm.nih.gov/pubmed/34698017
http://dx.doi.org/10.7554/eLife.69836

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