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Electron cryo-tomography reveals the subcellular architecture of growing axons in human brain organoids

During brain development, axons must extend over great distances in a relatively short amount of time. How the subcellular architecture of the growing axon sustains the requirements for such rapid build-up of cellular constituents has remained elusive. Human axons have been particularly poorly acces...

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Detalles Bibliográficos
Autores principales: Hoffmann, Patrick C, Giandomenico, Stefano L, Ganeva, Iva, Wozny, Michael R, Sutcliffe, Magdalena, Lancaster, Madeline A, Kukulski, Wanda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547956/
https://www.ncbi.nlm.nih.gov/pubmed/34698018
http://dx.doi.org/10.7554/eLife.70269